Cellular Therapies and Novel Blood Products in Trauma and Critical Care – The Future of Transfusion Medicine
Wednesday, December 11 | Barriers in Translation for Novel Products in Trauma and Critical Care
Discussion and talks will focus upon funding, translation, cell product production and processing
Badge and Materials Pickup
- Shibani Pati MD, PhD
CTTACC Conference Chair
Professor of Laboratory Medicine, UCSF
Scientific Director of Cellular Therapies
Session 1 | Sustainability of Research and Successful Translation of Novel Therapeutics in Trauma and Critical Care: from Bench to Bedside and Beyond
Discussion will focus upon funding support for the translational pipeline which includes the infrastructure needed for pre-clinical and clinical trials in trauma and critical care. Funding from federal sources, industry, philanthropy and venture capital will be discussed. Panelists will include representation from the NIH, BARDA, DOD, industry stakeholders and a venture capital firm.
Moderator(s)- Raymond Goodrich PhD
Executive Director, Infectious Disease Research Center
Office of the Vice President for Research
Professor, Department of Microbiology, Immunology and Pathology,
Colorado State University
- Geoffrey Ling MD, PhD
COL, USA, Ret.
Chief Executive Officer at SunQ, LLC
Ex Director and Founder of the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office - Keith Hoots MD
Director, Division of Blood Diseases and Resources
National Heart, Lung, and Blood Institute - Ken Kleinhenz
VP of Regulatory for Cellular Therapies
CSSi LifeSciences - Mary Homer PhD
Chief United States Radiological and Nuclear Countermeasures, Division of Chemical, Biological, Radiological, and Nuclear Countermeasures
Biomedical Advanced Research and Development Authority (BARDA) - Terry Opgenorth PhD
Vice President & Director of Launchpad
Colorado State University Ventures - Wilbur Malloy MA, MLS(ASCP)SBB
Lieutenant Colonel, US Army (Retired)
Health Science Program Manager
Hemorrhage and Resuscitation/Forward Surgical Care/Blood Products// Congressionally Directed Medical Research Program (CDMRP) US Army Medical Research and Development Command (MRDC)
Session 2 | Challenges in Product Development, Cell Production and Processing
Discussion will focus upon the translational barriers and challenges that exist in cell product production, development and processing. Panelists will include representation from the private industry, blood banks, NIH and academic centers involved in this space.
Moderator(s)- David McKenna MD
Professor of Transfusion Medicine
Director of the Division of Transfusion Medicine
University of Minnesota
- Dave Stroncek MD
Director for Center for Cellular Engineering, NIH Clinical Center
- Jonathan Esensten MD, PhD
Medical Director, UCSF HICTF and GMP Facility
Medical Director, Zuckerberg San Francisco General Hospital Blood Bank and Transfusion Service
Assistant Adjunct Professor, UCSF, Dept. of Laboratory Medicine
Moderator(s)
- Kenneth Bertram MD, PhD
Co-Chair CTTACC
COL, USA, Ret.
Professor of Regenerative Medicine
Wake Forest University
- Becky Cap
Sr. Vice President, Chief Operating Officer, GenCure
- Fabio Triolo D.d.R., M.Phil., PhD
Associate Professor of Clinical and Translational Sciences
Director, Cellular Therapy Core
Department of Pediatric Surgery
McGovern Medical School at UTHealth - Jon Rowley PhD
Chief Executive & Technology Officer, RoosterBio, Inc.
- Julie Allickson PhD
Director, Regenerative Medicine Clinical Center
Wake Forest Institute for Regenerative Medicine - Priya Baraniak PhD
Vice President, Corporate Development
OrganaBio, LLC - Robert Mays PhD
Vice President, Regenerative Medicine
Head of Neurosciences, Athersys, Inc.
Session 3 | Optimizing Cell Product Development and Delivery to Patients
Discussion will focus upon the current successes and challenges that exist in finalizing the end of product development which includes optimal cryopreservation, storage, shipping, handling and delivery of the final product to patients. These are areas that are critical for the success and safety of the products, clinical trials and final patient outcomes. Panelists will include representation from the private industry, blood banks and academic centers involved in this space.
Moderator(s)- Aby J. Mathew PhD
Senior VP & CTO
BioLife Solutions - Shibani Pati MD, PhD
CTTACC Conference Chair
Professor of Laboratory Medicine, UCSF
Scientific Director of Cellular Therapies
- Bob Harman DVM, MPVM
Chief Scientific Officer & Co-Founder of Personalized Stem Cells, Inc.
- Charles Cox MD
The George and Cynthia Mitchell Distinguished Chair in Neurosciences
Director, Children’s Program in Regenerative Medicine
Professor, Department of Pediatric Surgery
McGovern Medical School at UTHealth - Christopher Murphy
M SGT, USA, Ret.
President Combat Medical - David McKenna MD
Professor of Transfusion Medicine
Director of the Division of Transfusion Medicine
University of Minnesota - Donna Chang
President & CEO
Hope Biosciences - Fabio Triolo D.d.R., M.Phil., PhD
Associate Professor of Clinical and Translational Sciences
Director, Cellular Therapy Core
Department of Pediatric Surgery
McGovern Medical School at UTHealth
- Martin Schreiber MD
CTTACC Conference Co-Chair
COL, USAR
Professor of Surgery & Chief of Trauma, Critical Care & Acute Care Surgery
Oregon Health & Science University (OHSU)
- Geoffrey Ling MD, PhD
COL, USA, Ret.
Chief Executive Officer at SunQ, LLC
Ex Director and Founder of the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office
Thursday, December 12 | Transfusion Medicine in Trauma and Critical Care
The goal of this session is to discuss and understand pertinent issues in transfusion medicine and novel blood products related to the bleeding and acutely injured trauma patient. Topics of discussion will focus around novel blood products and adjuncts to resuscitation in bleeding patients.
Badge and Materials Pickup
- Shibani Pati MD, PhD
CTTACC Conference Chair
Professor of Laboratory Medicine, UCSF
Scientific Director of Cellular Therapies
Session 1 | Whole Blood – The First Cell Therapy in Trauma
- Paul Ness MD
Senior Director, Division of Transfusion Medicine
Professor of Pathology
Johns Hopkins University - Philip Spinella MD, FCCM
Professor of Pediatrics
Washington Univ School of Medicine St. Louis
- Martin Schreiber MD
CTTACC Conference Co-Chair
COL, USAR
Professor of Surgery & Chief of Trauma, Critical Care & Acute Care Surgery
Oregon Health & Science University (OHSU)
- Stacy Shackleford MD
Col, USAF MC
Joint Trauma System, Chief
DHA Combat Support
- Jason Sperry MD, MPH
Professor of Surgery and Critical Care
Director of Acute Care Surgery Fellowship
University of Pittsburgh
- Donald Jenkins MD
COL, USAF, Ret.
Professor of Surgery Uniformed Services University
Professor/Clinical, Division of Trauma and Emergency Surgery
Vice Chair for Quality, Department of Surgery UT San Antonio
Betty and Bob Kelso Distinguished Chair in Burn and Trauma Surgery
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Session 2 | Novel Resuscitation Adjuncts and Blood Products in Trauma
- Matthew Neal MD
Roberta G. Simmons Assistant Professor of Surgery
Assistant Professor of Clinical and Translational Science and Critical Care Medicine
University of Pittsburgh - Victor Macdonald PhD
SME Blood Products
USAMRMC
- Hasan Alam MD
Norman W. Thompson Professor of Surgery
Section Head of General Surgery
University of Michigan
- Ernest Moore MD
Professor of Surgery
Vice Chair of Research
Editor of Journal of Trauma and Acute Care Surgery
- Martin Schreiber MD
CTTACC Conference Co-Chair
COL, USAR
Professor of Surgery & Chief of Trauma, Critical Care & Acute Care Surgery
Oregon Health & Science University (OHSU)
- Joseph Rappold MD
Co-Chair CTTACC
CAPT, USN, Ret.
Professor of Surgery
Maine Medical Center Tufts University
- Karim Brohi MD
Professor of Trauma Sciences
Queen Mary University of London
Director London Major Trauma System
- Zafiris Zafirelis
Chief Executive Officer, Hemoglobin Oxygen Therapeutics LLC
Moderator(s)
- Joseph Rappold MD
Co-Chair CTTACC
CAPT, USN, Ret.
Professor of Surgery
Maine Medical Center Tufts University - Martin Schreiber MD
CTTACC Conference Co-Chair
COL, USAR
Professor of Surgery & Chief of Trauma, Critical Care & Acute Care Surgery
Oregon Health & Science University (OHSU)
- Andrew (Andre) Cap MD, PhD
COL, USA
Professor of Medicine
Uniformed Services University of the Health Sciences
Chief, Blood Research Program
US Army Institute for Surgical Research - Beth Shaz MD
President AABB
Chief Medical and Scientific Officer
Senior Vice President at New York Blood Center - Christophe Martinaud MD
Professor of Transfusion Medicine and Cell Therapy
French Military Blood Institute Clamart - Ernest Moore MD
Professor of Surgery
Vice Chair of Research
Editor of Journal of Trauma and Acute Care Surgery - Jason Sperry MD, MPH
Professor of Surgery and Critical Care
Director of Acute Care Surgery Fellowship
University of Pittsburgh - Karim Brohi MD
Professor of Trauma Sciences
Queen Mary University of London
Director London Major Trauma System
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Session 3 | Dried Plasma, Artificial RBCs and Pathogen Reduction of Blood
- Jeffrey McCullough MD
Emeritus Professor,
University of Minnesota - Richard Weiskopf MD
Professor Emeritus
University of California, San Francisco
- Rosemary Kozar MD, PhD
Professor of Surgery
Director of Translational Research Shock Trauma
University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center
- Larry Corash MD
Senior VP and Chief Scientific Officer Cerus Inc.
- Allan Doctor MD
Professor of Pediatrics, Biochemistry and Bioengineering
Director, Center for Blood Oxygen Transport and Hemostasis
University of Maryland School of Medicine
- Beth Shaz MD
President AABB
Chief Medical and Scientific Officer
Senior Vice President at New York Blood Center
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Session 4 | Novel Platelet and Platelet Derived Products
- Heather Pidcoke MD, PhD
Chief Medical Research Officer
Associate Director, Research
Translational Medicine Institute
Colorado State University - Lucy Kornblith MD
Assistant Professor of Surgery
Trauma Surgery and Surgical Critical Care
University of California San Francisco
Zuckerberg San Francisco General Hospital
- Mike Fitzpatrick PhD
COL, USA, Ret.
President & Director of Research and Development, Cellphire Inc.
- Karim Brohi MD
Professor of Trauma Sciences
Queen Mary University of London
Director London Major Trauma System
- Andrew (Andre) Cap MD, PhD
COL, USA
Professor of Medicine
Uniformed Services University of the Health Sciences
Chief, Blood Research Program
US Army Institute for Surgical Research
- Owen McCarty PhD
Professor and Chair of Department of Biomedical Engineering
Professor of Department of Cell & Development Biology
Oregon Health & Science University
- Shibani Pati MD, PhD
CTTACC Conference Chair
Professor of Laboratory Medicine, UCSF
Scientific Director of Cellular Therapies
- Alpa Mahuvakar Trivedi PhD
Research Professor
Department of Laboratory Medicine, UCSF
- Philip Spinella MD, FCCM
Professor of Pediatrics
Washington Univ School of Medicine St. Louis
Session 5 | Product Development, Support and Regulatory Approval of Novel Blood Products
Discussion will focus upon the current successes, challenges and translational barriers that exist in the development of novel blood products. Including dried plasma, dried platelets, dried cryoprecipitate, and more.
Moderator(s)- Kenneth Bertram MD, PhD
Co-Chair CTTACC
COL, USA, Ret.
Professor of Regenerative Medicine
Wake Forest University - Richard Gonzales MS, MT(ASCP)SBB
COL, USA, Ret.
President and CEO
Richblo2d Biologics Consulting Services LLC
- Andrew (Andre) Cap MD, PhD
COL, USA
Professor of Medicine
Uniformed Services University of the Health Sciences
Chief, Blood Research Program
US Army Institute for Surgical Research - Larry Corash MD
Senior VP and Chief Scientific Officer Cerus Inc.
- Mark Popovsky MD
Chief Medical Officer
Velico Medical, Inc - Mike Fitzpatrick PhD
COL, USA, Ret.
President & Director of Research and Development, Cellphire Inc. - Peter Marks MD, PhD
Director, Center for Biologics Evaluation and Research
U.S. Food and Drug Administration - Wilbur Malloy MA, MLS(ASCP)SBB
Lieutenant Colonel, US Army (Retired)
Health Science Program Manager
Hemorrhage and Resuscitation/Forward Surgical Care/Blood Products// Congressionally Directed Medical Research Program (CDMRP) US Army Medical Research and Development Command (MRDC) - Zafiris Zafirelis
Chief Executive Officer, Hemoglobin Oxygen Therapeutics LLC
Friday, December 13 | Cellular Therapies in Trauma and Critical Care Medicine
The goal of this session is to discuss and learn about the state of the science of cellular therapies in trauma and critical care. Pre-clinical and clinical studies will be presented in traumatic brain injury (TBI), Spinal Cord Injury (SCI), acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), cardiac disease, wound healing and tissue and bone regeneration.
Badge and Materials Pickup
Session 1 | Cellular Therapies in Critical Care Medicine
- Charles Cox MD
The George and Cynthia Mitchell Distinguished Chair in Neurosciences
Director, Children’s Program in Regenerative Medicine
Professor, Department of Pediatric Surgery
McGovern Medical School at UTHealth - Lauralyn McIntyre MD
Associate Professor in the Department of Medicine, University of Ottawa
Senior Scientist with the Clinical Epidemiology Department of the Ottawa Hospital Research Institute
- Joseph C. Wu MD, PhD
Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD
Professor of Medicine & Radiology Stanford University School of Medicine
- Anthony Atala MD
Professor of Surgery
Chair, Department of Urology
Director, Wake Forest Institute for Regenerative Medicine at Wake Forest University
- Michael Matthay MD
Professor of Pulmonary Critical Care Medicine
Associate Director of ICU
University of California San Francisco
- Daniel Weiss MD, PhD
Professor of Medicine
University of Vermont
ISCT Chief Scientific Officer
- Robert Mays PhD
Vice President, Regenerative Medicine
Head of Neurosciences, Athersys, Inc.
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Session 2 | Cellular Therapies in Neurotrauma and Organ Regeneration
- Deborah Stein MD
Professor and Chief of Surgery
Zuckerberg San Francisco General,
Vice Chair of Trauma and Critical Care Surgery
UCSF Department of Surgery - Hasan Alam MD
Norman W. Thompson Professor of Surgery
Section Head of General Surgery
University of Michigan
- Charles Cox MD
The George and Cynthia Mitchell Distinguished Chair in Neurosciences
Director, Children’s Program in Regenerative Medicine
Professor, Department of Pediatric Surgery
McGovern Medical School at UTHealth
- Ephron Rosenzweig PhD
Assistant Professor of Neurosciences
Center for Neural Repair
University of California San Diego
- Joel Martin MD
Senior Resident in Neurosurgery
University of California San Diego
- Erika Davies PhD
Health Scientist
Division of Chemical, Biological, Radiological, and Nuclear Countermeasures (DBRN)
Biomedical Advanced Research and Development Authority (BARDA)
- Peter Marks MD, PhD
Director, Center for Biologics Evaluation and Research
U.S. Food and Drug Administration
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Session 3 | Cellular Therapies for Wound Healing, Bone Healing and Burns
- Jan Nolta PhD
Director, Stem Cell Program and Institute for Regenerative Cures
University of California Davis Health
Scientific Director, UC Davis GMP Facility
Editor-in-Chief, Stem Cells - Samuel P. Carmichael II MD
Acute Care Surgery Fellow
Wake Forest Baptist Medical Center
- Clifford Lowell MD, PhD
Professor and Distinguished Chairman Department of Laboratory Medicine, UCSF
- Jan Nolta PhD
Director, Stem Cell Program and Institute for Regenerative Cures
University of California Davis Health
Scientific Director, UC Davis GMP Facility
Editor-in-Chief, Stem Cells
- Joy Wu MD
Assistant Professor of Medicine
Co Director Translational Investigator Program
Stanford University
- Christophe Martinaud MD
Professor of Transfusion Medicine and Cell Therapy
French Military Blood Institute Clamart
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Session 4 | New Technologies, Regulatory Issues and Challenges in the Field
- Michael Matthay MD
Professor of Pulmonary Critical Care Medicine
Associate Director of ICU
University of California San Francisco
- Tom Schulz PhD
VP of Manufacturing Sciences, Platelet BioGenesis
- Jürgen Schmitz PhD
Chief Scientific Officer
Miltenyi Biotec
- Biju Parekkadan PhD
Associate Professor, Biomedical Engineering, Rutgers University
Division Leader, Center for Surgery, Innovation, and Bioengineering, Harvard Medical School and Massachusetts General Hospital
Affiliated Faculty, Harvard Stem Cell Institute and the Broad Institute for Genetics
Co-Founder, Director, and Office of Chief Scientific Officer, Sentien Biotechnologies, Inc.
- Martin Schreiber MD
CTTACC Conference Co-Chair
COL, USAR
Professor of Surgery & Chief of Trauma, Critical Care & Acute Care Surgery
Oregon Health & Science University (OHSU) - Shibani Pati MD, PhD
CTTACC Conference Chair
Professor of Laboratory Medicine, UCSF
Scientific Director of Cellular Therapies
Presented by the University of California San Francisco Department of Laboratory Medicine
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